Wednesday, 28th August The Annual Scientific Meeting of the Australian Diabetes Society and the Australian Diabetes Educators Association 2013

Glucose Meters with Built-In Automated Bolus Calculator: Gadget or Real Value for Insulin-Treated Diabetic Patients?

A practical review of the paper published in Diabetes Therapy 2013 by Ides M. Colin and Isabelle Paris, followed by discussion and sharing of case studies around the value of bolus calculators. 

DO BGMs with a built-in bolus calculators improve the willingness and the ability of insulin-treated patients to make adequate therapeutic decisions and positively impact the metabolic control and the quality of life of users? Or are they simply a gimmick that will appeal to certain people with diabetes.

A panel of HCP’s involved in diabetes management will offer their perspectives and share case studies and experience.

Success in the next steps to prevent hypoglycaemia

Speaker: Clinical Professor Tim Jones 

Dr Jones is Head of Department of Diabetes and Endocrinology, Princess Margaret Hospital for Children, Perth, Clinical Professor at the Institute for Child Health Research, University of Western Australia and holds an NHMRC Practitioner Fellowship.  

This presentation includes a review of Low Glucose Suspend (LGS) integrated technology with new evidence showing the reduction of hypoglycaemia with sensor augmented pump therapy using automated insulin suspension. The clinical need to prevent hypoglycaemia will be emphasised given it is considered to be a major barrier to effective glycaemic control.  Professor Jones will also discuss new Australian research on impaired hypoglycaemia awareness, as well as specific populations suitable for sensor augmented pump therapy with automated insulin suspension. Given ongoing research towards developing the closed loop ‘artificial pancreas’ system, the presentation will also  focus on the progress  to date including Predictive Low Glucose Management (PLGM) theory combined with case studies from the PiLGriM study showing PLGM therapy in action.

Topics covered:

Topic 1: Update and review on Low Glucose Suspend (LGS)

Topic 2:  Hypo unawareness and specific indications

Topic 3:  A focus on new developments in preventing hypoglycaemia   

• Getting better at what we do: continuous quality improvement in a real world setting - Melinda Maryniuk

GP CME Eligible Session

• Type 2 Diabetes:  Insulin resistance or calorie resistance? - Philip Home

• The nuclear hormone receptor, Nor-1/NR4A3, regulates adiposity, substrate utilization and endurance - George Muscat
• Class IIa HDACs link skeletal muscle metabolic remodelling with muscle cell survival in type 2 diabetes - Sean L McGee
• The consequences of disrupting the expression of clock genes and circadian rhythms - David Kennaway

GP CME Eligible Session

• (Not too) Sweet young things. Metabolic disease, youth and antipsychotics. - Katherine Samaras
• Life-Stage Appropriate Care for Young Adults with Type 1 Diabetes - Katherine Kibbey
• Prader Willi Syndrome: management - Tania Markovic
• Cystic Fibrosis - Glynis Ross

• A Multiethnic study of diabetic retinopathy: poorer outcomes continue for Australian Aborigines and Pacific Islanders - Maria Constantino
• Ultra-Wide-Field Retinal Photography: Implications for Detection, Treatment and Study of Diabetic Retinopathy - Belinda Brooks
• Short-term dietary salt supplementation is not associated with reduced renal function in hypertensive subjects with type 2 diabetes mellitus - Angela X Chen
• Change in prevalence and associates of CKD in type 2 diabetes: The Fremantle Diabetes Study - Wendy A Davis
• Renal structure in normoalbuminuric and albuminuric patients with type 2 diabetes and impaired renal function - Elif I Ekinci
• A Comparison of Insulin Requirements in Women with Type 1 and Type 2 Diabetes During Pregnancy - Suja Padmanabhan

• Mentoring and Motivation: Perspectives of Australian Diabetes Educators on Professional Development: A Phenomenological Study - Maureen Kingston-Ray
• Acute-community collaboration strengthens services for people with complex Diabetes. - Rachel Miller
• Evaluation of the Chronic Condition Self-Management Support On-Line Learning Package - Ian Harmer
• “The association between glycemic control and health literacy in Aboriginal and Torres Strait Islanders with diabetes in Far North Queensland”. - Sean M Taylor

• Arginine Supplementation in Wound Healing: A Systematic Review  - Achamma Joseph
• Diabetes Education and Management: What do rural GPs think? - Pauline Hill
• UNDERSTANDING RULES AND RESPONSIBILITIES REGARDING DRIVING AMONGST A COHORT OF DIABETES PATIENTS AND THEIR HEALTH CARE PROFESSIONALS. - Cheryl Steele
• Point prevalence survey of complementary and alternative therapies use by hospital inpatients with diabetes - Trisha Dunning
• Diet soft drinks, water and risk of type 2 diabetes: a systematic review - Alan W Barclay

• Type 2 diabetes management with GLP-1 Exanatide (Byetta) in morbid obesity - Erika Urban
• Initial Outcomes of a patient insulin self-titration  model of care and selected clinical indicators. - Libby Bancroft
• Producing meaningful KPI’s for a High Risk Foot Service - Danielle Veldhoen
• High Risk Foot training in rural Western Australia: making a difference - Deborah E Schoen

• Measuring Insulin Resistance and Secretion in Humans - Allan Vaag
• Measurement of insulin secretion in humans - Jerry R Greenfield
• Of mice and men: assessing insulin sensitivity and insulin secretion in mice - Robert Lee-Young

• Accreditation of Diabetes Centres – the NADC application process  - Margaret McGill
• A Diabetes Clinic Database – why you need it and how to get it! - Peter Colman
• Diabetes Data, Quality, Audit and Benchmarking: [The Rise & Fall of ANDIAB 1993 – 2012] - Jeff Flack

• Can a Group Carbohydrate Counting Workshop reduce clinic waitlist and improve client knowledge? - Electra Ulrich
• Social barriers and enablers to Type 2 diabetes self-management: the role of capital - Rebecca Munt
• Diabetes: How much do you know? Empowering Chinese-Australians to manage diabetes. - Michelle Tong
• Multidisciplinary collaboration provides process-focussed education to increase GP confidence in using insulin therapy in type 2 diabetes (T2D) - Rosemary Macro
• DESMOND Down Under: the benefits of quality development for structured diabetes self management programs in Western Australia - Catherine Fung
• COMPARISON OF GROUP VERSUS INDIVIDUAL DIETARY EDUCATION FOR WOMEN WITH GESTATIONAL DIABETES - Robyn A Barnes
• GDM-GEM: GESTATIONAL DIABETES MELLITUS - GROUP EDUCATION MODEL: A REVIEW - Leah H Snape

• Diabetic Emergencies in a State-wide Australian Ambulance Service - Chin Yao Tan
• Anaerobic Exercise at Self-Report in Adults With Type 1 Diabetes Co-segregates With Increased Exercise Duration But Not With Hypoglycaemia: A Potential Role for Resistance Exercise in Limiting Hypoglycaemia - Agata Piotrowicz
• How problematic hypoglycaemia compromises quality of life - Christel Hendrieckx
• A lifetime perspective and risk of cognitive impairment in type 2 diabetes: Studies with the Fremantle Diabetes Study cohort - David G Bruce
• Diabetes, incident diabetes and impaired fasting glucose: 2-year effects on brain volume and cognition in the elderly. The Sydney Memory and Ageing Study - Katherine Samaras

• Client Service Delivery: Are we hitting the mark? - Christine Sullivan

Moderator: Michael D'Emden

Affirmative: Tim Davis

Negative: Stephen Colagiuri

• You2 - Live well with Gestational Diabetes - Udani Abeypala
• A PRIMARY CARE TEAM APPROACH TO INSULIN INITIATION AND TITRATION FOR PEOPLE WITH TYPE 2 DIABETES (T2D): THE STEPPING UP STUDY. - Louise Ginnivan
• Central Coast Local Health District Staff Knowledge of Diabetes - Brett Fenton
• Evaluation of Central Coast Local Health District Insulin Adjustment & Carbohydrate Counting Program - Brett Fenton
• Evaluation of Gestational Diabetes Mellitus Group Education and Individual Education via Interpreter. - Catherine Finneran
• Lifestyle modification and its effects of on metabolic parameters in patients with type 2 diabetes mellitus in a tertiary care hospital in Bangladesh - Samira Humaira Habib
• Pre-diabetes Referral Pathway - Marion Hawker
• RapidCalc Insulin Dose Calculator – patient feedback informs development - Brigid Knight
• MCAPL - a new joint mental health and diabetes clinic - Michelle Kriss
• Living the Insulin Pump Experience - Michelle. Kriss
• IS SHORT STATURE A RISK FACTOR FOR GESTATIONAL DIABETES MELLITUS? - sally meacock
• An electronic diabetes foot risk calculator - Deborah E Schoen
• REVIEW OF DIABETES TEAM-BASED CARE MODEL IN A COMMUNITY SETTING - Reeta Singh
• Early detection of impaired glucose tolerance in young adults - May Khin Soe Dr. May Soe
• Quick Access for Diabetes Clinic - Margaret Whillier

• 8-hydroxy-2-deoxy- Guanosine is not correlated to cholesterol level in prediabetes - Hayder Al-Aubaidy
• Live Simulator for Type 1 Diabetics - Simon Carter
• FAP ablation improves glucose tolerance, insulin resistance, liver steatosis and lipid metabolism in diet induced obese mice - Sumaiya Chowdhury
• Type 2 diabetes and Healthy Obesity: Ancestral and Derived Phenotypes? - Stephen Corbett
• Comparing high-throughput qPCR technologies for microRNA diagnostics: Does size matter? - Ryan J Farr
• ISOLATION AND IDENTIFICATION OF SIRTUIN SUBSTRATES USING A MODIFIED BIOTIN SWITCH STRATEGY - Hassina Massudi
• INCREASED C-PEPTIDE IN YOUNG SOUTH- AND SOUTH-EAST ASIAN FEMALES BUT NOT MALES WHO HAVE INCREASED NON-FASTING INSULIN - Maria Matuszek
• Effect of hyperglycaemia on the endothelial cells and the cytoprotective role of insulin and glutamine on the inflammatory cytokines and the mitohondria - Gracie Ong
• Comparative analysis of multiple approaches for generating new pancreas from old - Wilson Wong
• The role of seipin in adipocyte differentiation and lipid droplet formation - H. Rob Yang
• Oligosaccharyltransferase-48 as a Novel Mediator of Chronic Kidney Disease in Diabetes - Aowen Zhuang

GP CME Eligible Session

Hear from Dr Jones about the benefits of Insulin Pump Therapy in managing hypoglycaemia

• Pathway and progress towards preventing hypoglycaemia - Tim Jones

Delegates involved in the poster discussion are required to stand by their poster on Wednesday 28th August from 1:30 PM – 2:00 PM. Presentations will be in 5 minute slots – 3 minutes to summarise research and 2 minutes to answer any questions.

Beta-Cell Chairperson - Kathryn Aston-Mourney

Complications Chairperson - Josephine Forbes

Immunology/Stem cells Chairperson - Charmaine Simeonovic

Adipose Tissue/Fatty Acids Chairperson - Andrew Hoy

Insulin Action Chairperson - Matthew Watt

Glucose Uptake/Homeostasis - Jiming Ye

• Id1 and Id3 regulate redox status and beta-cell survival under conditions of oxidative stress - Mohammed Bensellam
• Inflammation induced ZIP14 transporter upregulated in pancreatic islets of type 2 diabetic db/db mice - Mariea Bosco
• Glucose intolerance is a very early defect that predates profound hyperinsulinemia in high fat-fed obese foz/foz mice on the NOD.B10 background - Viviane Delghingaro-Augusto
• Deletion of β-cell ARNT (Aryl hydrocarbon Receptor Nuclear Translocator) Causes Islet Transplant Failure - Amit Lalwani
• LYSOSOMAL LIPID METABOLISM IS A NOVEL REGULATOR OF INSULIN SECRETION. - Gemma L Pearson
• Redox imbalance and endothelial DNA damage as early markers of atherosclerosis risk in prediabetes - Hayder Al-Aubaidy
• Altered NGAL Levels in Diabetic Kidney Disease: A Potential Marker for Tubular Damage - Ernuo Cheng
• Protection Against Progression of Non-Alcoholic Steatohepatitis (NASH) by Sitagliptin In Type 2 Diabetes  - Jing Ren
•  Effects of Aqueous Extract of Momordica charantia L. on Wound Healing in a Streptozotocin Induced Model of Type II Diabetes  - Alireza Rezaeizadeh
• Differential Profiles of Fenofibrate and Liraglutide on Pro-fibrotic and Pro-inflammatory Changes in a Murine Model of Diabetic Cardiomyopathy - Xiaoyu Wang
• Selected cell populations of the kidney present differing metabolic profiles which are further altered under hyperglycaemic conditions. - Micheal S Ward
• Reduced autoimmune diabetes incidence via glycotoxin lowering therapies is time dependent in an experimental diabetic mouse model - Danielle J Borg
• Role of pro-apoptotic molecule "bid" in immune-mediated human beta-cell death - Mugdha Joglekar
• Derivation, characterization and differentiation of human gallbladder-derived islet progenitor cells - Sarang Satoor
• Secreted proteins from the helminth parasite Fasciola hepatica modulate the immune environment to prevent autoimmune diabetes - Maria E Lund
• Deficiency in type I interferon signalling prevents the early interferon-gene signature in pancreatic islets but not type 1 diabetes in non-obese diabetic mice. - Hong Sheng Quah
• Adipose-derived Mesenchymal Cell Derivation, Characterization and Differentiation for potential use in cell replacement therapy for Diabetes - Michael Williams
• Deletion of Acetyl-CoA Carboxylase 2 (ACC2) does not alter insulin sensitivity despite increased fatty acid oxidation in 9-12 month old mice - Amanda Brandon
• Browning of human subcutaneous adipose tissue progenitor cells in lean and obese adults. - Andrew L Carey
• Adipose tissue and non-alcoholic steatohepatitis in high fat-fed foz/foz mice - Tenzin Dagpo
• Understanding a bug's life in the fat land - Holly D Kristensen
• Fatty acid oxidation and storage in the hypothalamic parenchyma of mice is limited by transport across the blood brain barrier - Vanessa R Haynes
• Integrated Systems Analysis of Insulin Resistance Reveals Cholesterol Homeostasis to be a Key Determinant of Insulin Sensitivity - Daniel Fazakerley
• THE MODULATION OF HEPATIC INSULIN ACTION AND LIPID METABOLISM BY PROTEIN KINASE C ISOFORMS - Mana (Bing Qing) Liao
• Diet is a more potent regulator of the total liver proteome than ageing - Christopher Meoli
• Amelioration of the ER-stress associated IRE-1 signalling pathway, but not the PERK pathway, correlates with restoration of insulin sensitivity in liver cells. - Juan C Molero
• Sodium-derived muscle insulin resistance is caused by a loss of microvascular insulin sensitivity that can be restored with ACE inhibition. - Dino Premilovac
• Optimization of conditional glycogen synthase deletion in skeletal muscle in mice. - Chrysovalantou E. Xirouchaki
• Kaempferol, a dietary flavonoid improves glucose homeostasis in streptozotocin diabetic tissues by altering glycolytic and gluconeogenic enzymes - Khalid S Al-Numair
• NOS Inhibition Does Not Attenuate the Increase in Muscle Glucose Uptake During Contraction in Sprague Dawley Rats - Andrew C Betik
• Isolation and identification of a novel anti-diabetic compound of 3-hydroxymethyl xylitol (3-HMX) from Casearia esculenta (Roxb.) root, on key carbohydrate metabolic enzymes, lipid peroxides and antioxidants in streptozotocin-induced diabetic rats - Chandramohan Govindasamy
• NOS inhibition attenuates the increase in mouse skeletal muscle glucose uptake during contraction independently of nNOSμ - Yet Hoi Hong
• The Small Molecule Sophocarpidine as a Potential Novel Drug for Insulin Resistant State Targeting the Liver - Xiao-Yi Zeng

GP CME Eligible Session

• Lessons learned from Imaging, Atherosclerotic Plaque in the Diabetic patient - Stephen Nicholls

Everything you wanted to know about how to use data to improve your performance and service delivery.

• Without data it’s just an opinion - Trisha Dunning
• Without an Understanding of Purpose and Context Data is Blind: The Development of a Model of Care Toolkit - Kenneth Walsh
• Title to be provided - Tony Holland
• Delivering Quality Diabetes Education: Standards and Guidelines - Melinda Maryniuk

‘Australia’s cultural diversity is one of our greatest strengths, it is at the heart of who we are’ and continues to grow.

Cultural competency is essential for services provided in all localities to avoid further marginalising this important part of our community.  

 This symposium will define cultural competence, provide an interactive workshop and relevant resources.

• Cultural Competence: A shared responsibility - Peter Abraham
• Cultural frameworks and their relevance to diabetes education - Kerry Taylor
• Culturally appropriate resources: National Diabetes Services Scheme - Emily D'Amico

Presented by John Turtle and Hal Breidahl

ADS Founders Awards to be presented at the conclusion of this lecture.

An exciting exploration of the newly released Australian dietary guidelines, an insider’s guide to carbohydrate counting in practice plus a first-look at new tools for determining insulin dose.

• How the new Australian Dietary Guidelines apply to people with diabetes - Kate Marsh
• Practicalities of Carbohydrate Counting - Carmel Smart
• Alternative Methods for Determining Mealtime Insulin Dose - Kirstine Bell

Creative approaches to writing up your work from proposal to publication. Let those with experience give you tips on getting noticed.

• Tips for Successful Grant Writing - Ruth Colagiuri
• Let's write it up; Getting your ideas noticed - Nick Hopwood
• Principles of writing for publication - Jennie Brand-Miller

Chair: Alicia Jenkins

• Hepatic Steatosis, Dyslipoproteinaemia and Cardiometabolic Disease - Gerald F Watts
• Could HDL Therapies Have a Role in the Management of Diabetes? - Bronwyn A Kingwell
• Lipids in The Management of Diabetes - Richard O'Brien

• PET imaging of the native and transplanted islets of Langerhans - Olle Korsgren
• Results of the Australian Multi-Centre Trial of Clinical Islet Transplantation - Philip J O'Connell
• Reversal of type 1 diabetes by islet transplantation - Tom Kay

GP CME Eligible Session

• Supporting self-management and optimising mental health in people with type 1 diabetes: an education resource for trainees in adult endocrinology - Jennifer J Conn
• Mechanisms of Antipsychotic Metabolic Derangements - Timothy Lambert
• Exercise Interventions in Depression and Mental Illness: Fact or Fiction - Simon Rosenbaum

• Development of a Novel Technique for the Fast Assessment of Peripheral Insulin Action in Conscious and Non-Constrained Small Animals - Xiao-Yi Zeng
• Perilipin 5 deficiency in mice alters fatty acid metabolism and causes skeletal muscle insulin resistance - Rachael Mason
• IC7: an IL6-CNTF chimera improves obesity induced glucose intolerance - Tamara Allen
• Doc2B: Multiple Sites of Action in GLUT4 Exocytosis - James G Burchfield
• Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes - Pierre Scotney
• The RabGAP TBC1D1 plays a central role in exercise regulated glucose metabolism in skeletal muscle - Jacqueline Stoeckli

• Glycemic Control and Treatment Satisfaction in Type 2 Diabetes: Basal Plus compared with Biphasic Insulin in the LANSCAPE Trial - Neale Cohen
• What really happens when patients with Type 2 diabetes (T2DM) are commenced on insulin –longitudinal changes in HbA1c from initiation to 4 years - from the Australian S4S-DINGO – Diabetes Informatics Group - David M Hoffman
• Predictors of good blood glucose control in people receiving biphasic insulin aspart 30 premix insulin: data from the A₁chieve study - Philip Home
• Improved glycaemic control without increased hypoglycaemia incidence and weight gain with insulin-vildagliptin combination therapy in Asian patients with type 2 diabetes - Richard Simpson
• Exenatide once weekly: Sustained glycaemic and weight control through 3 years compared with insulin glargine - Stephen Stranks